Vr Adviser 13F annual report

Vr Adviser is an investment fund managing more than $2.1 trillion ran by Sherman Souther. There are currently 38 companies in Mr. Souther’s portfolio. The largest investments include Apogee Therapeutics Inc and 4d Molecular Therapeutics In, together worth $705 billion.

Limited to 30 biggest holdings

$2.1 trillion Assets Under Management (AUM)

As of 8th May 2024, Vr Adviser’s top holding is 8,493,321 shares of Apogee Therapeutics Inc currently worth over $564 billion and making up 26.8% of the portfolio value. In addition, the fund holds 4,400,000 shares of 4d Molecular Therapeutics In worth $140 billion. The third-largest holding is Ocular Therapeutix Inc worth $116 billion and the next is Spyre Therapeutics Inc worth $82.4 billion, with 2,171,782 shares owned.

Currently, Vr Adviser's portfolio is worth at least $2.1 trillion. The total portfolio value may be much higher due to cash assets that are not publicly disclosed such as fixed income, real estate, or cash equivalents.

Careers at Vr Adviser

The Vr Adviser office and employees reside in New York, New York. According to the last 13-F report filed with the SEC, Sherman Souther serves as the Authorized Signatory at Vr Adviser.

Recent trades

In the most recent 13F filing, Vr Adviser revealed that it had opened a new position in Apogee Therapeutics Inc and bought 8,493,321 shares worth $564 billion.

The investment fund also strengthened its position in Merus N.V by buying 564,000 additional shares. This makes their stake in Merus N.V total 1,790,214 shares worth $80.6 billion. Merus N.V soared 113.6% in the past year.

On the other hand, there are companies that Vr Adviser is getting rid of from its portfolio. Vr Adviser closed its position in Aclaris Therapeutics Inc on 15th May 2024. It sold the previously owned 4,563,962 shares for $71.9 billion. Sherman Souther also disclosed a decreased stake in Cabaletta Bio Inc by 0.2%. This leaves the value of the investment at $26.7 billion and 1,563,952 shares.

One of the largest hedge funds

The two most similar investment funds to Vr Adviser are Chilton Capital Management and Fj Investments. They manage $2.1 trillion and $2.1 trillion respectively.


Sherman Souther investment strategy

Vr Adviser’s portfolio is diversified across 2 sectors. Currently, their heaviest sector is Health Care — making up 36.6% of the total portfolio value. The fund focuses on investments in the United States as 47.4% of the portfolio companies are based in the United States.

The majority of the companies in the fund’s portfolio are small-cap stocks. Stocks with a size of more than $100 million in market cap make up 21% of the total holdings value. On the other hand, large-cap stocks make up only approximately 0.1% of the portfolio. The average market cap of the portfolio companies is close to $334 million.

The complete list of Vr Adviser trades based on 13F SEC filings

These positions were updated on May 15th based on the fund’s latest 13F filing. Quickly find out what the most recently closed or increased positions are.

Security Shares Owned Value Allocation
Apogee Therapeutics Inc
Opened
8,493,321
$564,381,180,000 26.85%
4d Molecular Therapeutics In
Opened
4,400,000
$140,184,000,000 6.67%
Ocular Therapeutix Inc
Opened
12,762,462
$116,138,404,000 5.52%
Spyre Therapeutics Inc
Opened
2,171,782
$82,375,691,000 3.92%
Merus N.V
46.00%
1,790,214
$80,613,336,000 3.83%
Pharvaris N V
Opened
3,395,606
$78,472,455,000 3.73%
KalVista Pharmaceuticals Inc
114.28%
6,249,731
$74,121,810,000 3.53%
Aclaris Therapeutics Inc
Closed
4,563,962
$71,882,402,000
Enliven Therapeutics Inc
Opened
4,026,331
$70,823,162,000 3.37%
Viridian Therapeutics Inc
43.81%
3,882,671
$67,985,569,000 3.23%
Dianthus Therapeutics Inc
Opened
2,094,373
$62,831,190,000 2.99%
Dyne Therapeutics, Inc.
Opened
2,173,913
$61,717,390,000 2.94%
Applied Therapeutics, Inc.
Opened
9,075,000
$61,710,000,000 2.94%
Oric Pharmaceuticals, Inc.
Opened
4,394,527
$60,424,746,000 2.87%
Axsome Therapeutics Inc
Closed
670,718
$51,732,479,000
Astria Therapeutics Inc
Opened
3,608,645
$50,791,678,000 2.42%
Mersana Therapeutics Inc
Opened
11,328,000
$50,749,440,000 2.41%
Engene Holdings Inc
Opened
2,565,841
$43,491,005,000 2.07%
Praxis Precision Medicines I
Opened
706,126
$43,087,809,000 2.05%
Hillevax Inc
Opened
2,075,000
$34,507,250,000 1.64%
Cogent Biosciences, Inc.
27.02%
5,129,167
$34,468,002,000 1.64%
Gh Research Plc
Closed
3,517,125
$34,186,455,000
Edgewise Therapeutics Inc
Opened
1,818,182
$33,163,640,000 1.58%
Dbv Technologies S A
Closed
9,300,000
$29,257,800,000
Cabaletta Bio Inc
17.48%
1,563,952
$26,681,021,000 1.27%
Arvinas Inc
Opened
627,788
$25,915,089,000 1.23%
Taysha Gene Therapies, Inc.
Opened
9,000,000
$25,830,000,000 1.23%
Dice Therapeutics Inc
Closed
819,000
$25,552,800,000
Aquestive Therapeutics Inc
Opened
5,555,555
$23,666,664,000 1.13%
Terns Pharmaceuticals Inc
8.03%
3,410,058
$22,369,980,000 1.06%
Adverum Biotechnologies Inc
Opened
1,556,419
$22,007,765,000 1.05%
Aerovate Therapeutics Inc
Closed
747,869
$21,912,562,000
Celcuity Inc
53.93%
970,000
$20,952,000,000 1.00%
Pliant Therapeutics, Inc.
Closed
1,080,000
$20,876,400,000
Novavax, Inc.
Closed
1,879,894
$19,325,310,000
Abivax Sa
Opened
1,345,780
$19,244,654,000 0.92%
Immatics N.v
Opened
1,750,000
$18,392,500,000 0.87%
Annexon Inc
Closed
3,220,050
$16,647,659,000
Vectivbio Hldg Ag
Closed
1,866,000
$16,168,890,000
Lyra Therapeutics, Inc.
178.75%
2,576,093
$16,023,298,000 0.76%
Cg Oncology Inc
Opened
350,000
$15,365,000,000 0.73%
Century Therapeutics Inc
Opened
3,405,133
$14,233,456,000 0.68%
Provention Bio, Inc.
Closed
1,118,653
$11,824,162,000
Trevi Therapeutics, Inc.
12.22%
3,422,675
$11,808,229,000 0.56%
Savara Inc
Closed
6,351,531
$9,844,873,000
Milestone Pharmaceuticals In
Closed
2,208,812
$8,746,896,000
Tenaya Therapeutics Inc
Opened
1,555,556
$8,135,558,000 0.39%
Lianbio
Closed
4,793,047
$7,860,597,000
Mineralys Therapeutics Inc
Opened
555,554
$7,172,202,000 0.34%
Marinus Pharmaceuticals Inc
Closed
1,770,705
$7,047,406,000
Acelyrin Inc
Opened
937,113
$6,325,513,000 0.30%
EyePoint Pharmaceuticals Inc
Opened
250,000
$5,167,500,000 0.25%
Fulcrum Therapeutics Inc
Closed
447,326
$3,256,533,000
Inozyme Pharma, Inc.
Closed
2,709,987
$2,845,486,000
Atyr Pharma Inc
Closed
1,171,436
$2,565,445,000
Affimed N.V.
Closed
1,428,571
$1,771,428,000
Rallybio Corp
Closed
268,532
$1,764,255,000
Olema Pharmaceuticals, Inc.
Opened
77,042
$872,115,000 0.04%
No transactions found
Showing first 500 out of 58 holdings