Soleus Capital Management, L.P. 13F annual report

Soleus Capital Management, L.P. is an investment fund managing more than $1.13 trillion ran by Harold Schaaff. There are currently 92 companies in Mr. Schaaff’s portfolio. The largest investments include TG Therapeutics Inc and Iovance Biotherapeutics Inc, together worth $125 billion.

Limited to 30 biggest holdings

$1.13 trillion Assets Under Management (AUM)

As of 7th August 2024, Soleus Capital Management, L.P.’s top holding is 3,645,562 shares of TG Therapeutics Inc currently worth over $64.9 billion and making up 5.7% of the portfolio value. Relative to the number of outstanding shares of TG Therapeutics Inc, Soleus Capital Management, L.P. owns more than approximately 0.1% of the company. In addition, the fund holds 7,548,000 shares of Iovance Biotherapeutics Inc worth $60.5 billion, whose value grew 12.5% in the past six months. The third-largest holding is United Therapeutics Corp worth $45.1 billion and the next is Nurix Therapeutics worth $42.9 billion, with 2,055,916 shares owned.

Currently, Soleus Capital Management, L.P.'s portfolio is worth at least $1.13 trillion. The total portfolio value may be much higher due to cash assets that are not publicly disclosed such as fixed income, real estate, or cash equivalents.

Careers at Soleus Capital Management, L.P.

The Soleus Capital Management, L.P. office and employees reside in Greenwich, Connecticut. According to the last 13-F report filed with the SEC, Harold Schaaff serves as the Chief Compliance Officer, Soleus Capital Management, L.P. at Soleus Capital Management, L.P..

Recent trades

In the most recent 13F filing, Soleus Capital Management, L.P. revealed that it had opened a new position in Terns Pharmaceuticals Inc and bought 4,947,738 shares worth $33.7 billion.

The investment fund also strengthened its position in TG Therapeutics Inc by buying 477,106 additional shares. This makes their stake in TG Therapeutics Inc total 3,645,562 shares worth $64.9 billion. TG Therapeutics Inc soared 91.3% in the past year.

On the other hand, there are companies that Soleus Capital Management, L.P. is getting rid of from its portfolio. Soleus Capital Management, L.P. closed its position in HCA Healthcare Inc on 14th August 2024. It sold the previously owned 51,441 shares for $17.2 billion. Harold Schaaff also disclosed a decreased stake in United Therapeutics Corp by 0.5%. This leaves the value of the investment at $45.1 billion and 141,499 shares.

One of the average hedge funds

The two most similar investment funds to Soleus Capital Management, L.P. are Private Ocean and Ascent. They manage $1.13 trillion and $1.13 trillion respectively.


Harold Schaaff investment strategy

Soleus Capital Management, L.P.’s portfolio is diversified across 4 sectors. Currently, their heaviest sector is Health Care — making up 74.3% of the total portfolio value. The fund focuses on investments in the United States as 53.3% of the portfolio companies are based in the United States.

The majority of the companies in the fund’s portfolio are small-cap stocks. Stocks with a size of more than $100 million in market cap make up 11% of the total holdings value. On the other hand, large-cap stocks make up only 7.6% of the portfolio. The average market cap of the portfolio companies is close to $6.83 billion.

The complete list of Soleus Capital Management, L.P. trades based on 13F SEC filings

These positions were updated on August 14th based on the fund’s latest 13F filing. Quickly find out what the most recently closed or increased positions are.

Security Shares Owned Value Allocation
TG Therapeutics Inc
15.06%
3,645,562
$64,854,548,000 5.72%
Iovance Biotherapeutics Inc
115.35%
7,548,000
$60,534,960,000 5.34%
United Therapeutics Corp
45.52%
141,499
$45,074,506,000 3.97%
Nurix Therapeutics, Inc.
84.39%
2,055,916
$42,906,967,000 3.78%
EDAP TMS S.A.
0.92%
7,293,728
$39,677,880,000 3.50%
Terns Pharmaceuticals Inc
Opened
4,947,738
$33,694,096,000 2.97%
Revolution Medicines Inc
17.49%
856,178
$33,228,268,000 2.93%
Surmodics, Inc.
2.38%
781,777
$32,865,905,000 2.90%
Organogenesis Holdings Inc.
20.33%
11,518,954
$32,253,071,000 2.84%
Jasper Therapeutics Inc
7.51%
1,276,190
$28,969,513,000 2.55%
IDEAYA Biosciences, Inc.
30.09%
694,069
$24,368,763,000 2.15%
Axogen Inc.
6.44%
3,305,815
$23,934,101,000 2.11%
Krystal Biotech Inc
49.82%
126,000
$23,138,640,000 2.04%
Merus N.V
92.42%
376,321
$22,266,914,000 1.96%
Penumbra Inc
44.05%
123,450
$22,217,297,000 1.96%
Essa Pharma Inc
17.30%
4,210,537
$22,147,425,000 1.95%
Praxis Precision Medicines I
1,330.22%
533,015
$22,045,500,000 1.94%
Celcuity Inc
30.04%
1,211,187
$19,839,243,000 1.75%
Inari Med Inc
47.43%
408,373
$19,663,160,000 1.73%
BeiGene Ltd
7.02%
137,700
$19,645,659,000 1.73%
C4 Therapeutics, Inc.
64.78%
4,051,996
$18,720,222,000 1.65%
Castle Biosciences, Inc.
17.67%
853,628
$18,583,482,000 1.64%
Neuropace Inc
No change
2,433,168
$18,394,750,000 1.62%
Enliven Therapeutics Inc
Opened
769,263
$17,977,676,000 1.59%
Alnylam Pharmaceuticals Inc
Opened
71,700
$17,423,100,000 1.54%
HCA Healthcare Inc
Closed
51,441
$17,157,117,000
Syndax Pharmaceuticals Inc
123.98%
826,500
$16,968,045,000 1.50%
Humana Inc.
38.40%
44,356
$16,573,619,000 1.46%
GSK Plc
30.01%
415,000
$15,977,500,000 1.41%
Treace Med Concepts Inc
75.80%
2,365,648
$15,731,559,000 1.39%
Biogen Inc
Closed
72,800
$15,697,864,000
Vaxcyte, Inc.
10.83%
185,250
$13,988,228,000 1.23%
10x Genomics, Inc.
Opened
719,000
$13,984,550,000 1.23%
Rigel Pharmaceuticals
Closed
9,241,986
$13,678,139,000
Cg Oncology Inc
94.88%
424,585
$13,404,148,000 1.18%
Nuvalent Inc
32.87%
171,788
$13,031,838,000 1.15%
Evolus Inc
620.00%
1,152,000
$12,499,200,000 1.10%
Enanta Pharmaceuticals Inc
37.72%
799,546
$10,370,112,000 0.91%
Alector, Inc.
Opened
2,239,006
$10,165,087,000 0.90%
Keros Therapeutics, Inc.
19.01%
221,600
$10,127,120,000 0.89%
Teva Pharmaceutical Inds Ltd
83.18%
586,499
$9,530,609,000 0.84%
Arcellx Inc
13.83%
170,741
$9,423,196,000 0.83%
Inhibrx, Inc.
Closed
267,871
$9,364,770,000
Biodesix Inc
Opened
6,111,964
$9,351,305,000 0.82%
Tango Therapeutics Inc
22.24%
1,049,895
$9,008,099,000 0.79%
OrthoPediatrics corp
Opened
309,500
$8,901,220,000 0.78%
Rigel Pharmaceuticals
Opened
1,043,697
$8,579,189,000 0.76%
Bausch Health Cos Inc
80.00%
1,206,000
$8,405,820,000 0.74%
Immunic, Inc.
No change
7,293,007
$8,095,238,000 0.71%
Y-Mabs Therapeutics Inc
13.49%
647,982
$7,827,623,000 0.69%
Engene Holdings Inc
No change
800,000
$7,544,000,000 0.67%
Pharvaris N V
0.61%
399,430
$7,509,284,000 0.66%
Avadel Pharmaceuticals plc
Opened
509,000
$7,156,540,000 0.63%
Dyne Therapeutics, Inc.
Opened
201,000
$7,093,290,000 0.63%
Mannkind Corp
Closed
1,558,537
$7,060,173,000
Mind Medicine Mindmed Inc
Closed
750,237
$7,052,228,000
Cvrx Inc
1,110.51%
587,098
$7,039,305,000 0.62%
Insmed Inc
59.01%
102,472
$6,865,624,000 0.61%
Hims & Hers Health, Inc.
Opened
333,000
$6,723,270,000 0.59%
Theratechnologies Inc.
No change
4,801,376
$6,721,926,000 0.59%
Immunovant Inc
4.82%
251,900
$6,650,160,000 0.59%
Adaptive Biotechnologies Cor
Opened
1,720,000
$6,226,400,000 0.55%
Applied Therapeutics, Inc.
18.86%
1,269,714
$5,929,564,000 0.52%
Globus Med Inc
Opened
86,000
$5,890,140,000 0.52%
Jazz Pharmaceuticals plc
Opened
53,935
$5,756,483,000 0.51%
Viking Therapeutics Inc
Closed
67,121
$5,503,922,000
BioAtla, Inc.
4.03%
3,901,314
$5,344,800,000 0.47%
Erasca Inc
Opened
2,162,162
$5,102,702,000 0.45%
Verastem Inc
7.83%
1,661,297
$4,950,665,000 0.44%
COMPASS Pathways plc
Closed
565,550
$4,705,376,000
KalVista Pharmaceuticals Inc
Closed
386,000
$4,577,960,000
Regulus Therapeutics Inc
Closed
1,562,500
$4,500,000,000
Mereo BioPharma Group plc
52.35%
1,246,953
$4,489,031,000 0.40%
Iradimed Corp
71.78%
102,067
$4,484,824,000 0.40%
Viridian Therapeutics Inc
No change
340,000
$4,423,400,000 0.39%
Exact Sciences Corp.
Opened
91,611
$3,870,565,000 0.34%
Insulet Corporation
Opened
18,800
$3,793,840,000 0.33%
Kiniksa Pharmaceuticals Intl
Opened
200,000
$3,734,000,000 0.33%
InspireMD Inc
No change
1,378,128
$3,438,843,000 0.30%
Nkarta, Inc.
Closed
300,000
$3,243,000,000
Calcimedica Inc
No change
783,904
$3,104,260,000 0.27%
The Beauty Health Company
843.95%
1,604,718
$3,081,059,000 0.27%
Sanofi
Opened
62,500
$3,032,500,000 0.27%
Dianthus Therapeutics Inc
Closed
100,000
$3,000,000,000
Fate Therapeutics Inc
No change
870,000
$2,853,600,000 0.25%
Taysha Gene Therapies, Inc.
Closed
925,000
$2,654,750,000
X4 Pharmaceuticals, Inc.
11.55%
4,051,000
$2,349,580,000 0.21%
Olema Pharmaceuticals, Inc.
67.10%
216,500
$2,342,530,000 0.21%
Janux Therapeutics Inc
64.83%
55,500
$2,324,895,000 0.21%
4d Molecular Therapeutics In
44.90%
108,598
$2,279,472,000 0.20%
Genedx Holdings Corp
88.89%
87,000
$2,274,180,000 0.20%
Arcutis Biotherapeutics Inc
Closed
225,000
$2,229,750,000
Cervomed Inc
No change
126,614
$2,167,632,000 0.19%
AVITA Medical Inc
256.00%
267,000
$2,114,640,000 0.19%
Annexon Inc
Closed
292,400
$2,096,508,000
NovoCure Ltd
84.35%
108,900
$1,865,457,000 0.16%
Apogee Therapeutics Inc
Closed
20,000
$1,329,000,000
Inhibrx Biosciences Inc
Opened
88,470
$1,253,620,000 0.11%
TransMedics Group, Inc.
Closed
16,700
$1,234,798,000
Oric Pharmaceuticals, Inc.
61.28%
163,000
$1,152,410,000 0.10%
Adverum Biotechnologies Inc
Opened
147,246
$1,010,108,000 0.09%
Protagonist Therapeutics Inc
Closed
34,500
$998,085,000
Denali Therapeutics Inc
Closed
47,000
$964,440,000
Amicus Therapeutics Inc
Closed
57,966
$682,839,000
Establishment Labs Holdings Inc
Opened
15,000
$681,600,000 0.06%
Orthofix Med Inc
Opened
51,000
$676,260,000 0.06%
Tenaya Therapeutics Inc
Closed
122,222
$639,221,000
MiMedx Group, Inc
Opened
82,884
$574,386,000 0.05%
Aadi Bioscience Inc
Opened
333,227
$486,511,000 0.04%
Bicycle Therapeutics plc
84.64%
23,500
$475,640,000 0.04%
Natera Inc
95.86%
3,600
$389,844,000 0.03%
Io Biotech Inc
Opened
192,670
$225,424,000 0.02%
Silk Rd Med Inc
Closed
10,000
$183,200,000
UroGen Pharma Ltd
Closed
10,000
$150,000,000
Liquidia Corp
Closed
10,000
$147,500,000
Xeris Biopharma Holdings Inc
No change
62,083
$139,687,000 0.01%
No transactions found
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